Have asthma? You likely have an allergy as well

Tuesday, April 2, 2013

Asthma is becoming an epidemic in the United States. The number of Americans diagnosed with asthma grows annually, with 26 million currently affected. And according to a new study, nearly two-thirds or more of all asthmatics also have an allergy, which can make this spring season particularly bothersome.

The study, which is published in the April issue of Annals of Allergy, Asthma & Immunology, the scientific journal of the American College of Allergy, Asthma and Immunology (ACAAI), found that an astonishing 75 percent of asthmatic adults aged 20- to 40-years-old, and 65 percent of asthmatic adults aged 55 years and older, have at least one allergy.

"Allergists have known the prevalence of allergies among asthmatic children is high at 60 to 80 percent, but it was thought allergies were not as common in asthmatic adults," said allergist Paula Busse, MD, lead study author. "These findings are important, and can help lead to proper diagnosis and treatment."

A total of 2,573 adults were studied in a National Health and Nutrition Examination Survey (NHANES). A panel of 19 allergens was used to detect allergy among asthmatics.

While asthma is frequently associated with children, it is not uncommon among adults 60 years and older, affecting three to seven percent. This number is likely higher, however, because asthma is often underdiagnosed in older adults.

"Both asthma and allergies can strike at any age, and are serious diseases," said allergist Richard Weber, MD, ACAAI president. "Anyone who thinks they may be having symptoms of an allergy or asthma should see a board-certified allergist. Allergists are experts in diagnosing and treating both conditions."

According to the ACAAI, more than 50 million Americans have an allergy, a number which is also on the rise. Is the link between asthma and allergies a reason?

"It could be one of many creating this perfect storm for allergies," said Dr. Weber. "Other factors, such as the hygiene hypothesis, climate change and an increase in awareness and education can also be reasons for this growth."

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American College of Allergy, Asthma, and Immunology: http://www.acaai.org/Pages/default.aspx

Thanks to American College of Allergy, Asthma, and Immunology for this article.

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Source: http://www.labspaces.net/127553/Have_asthma__You_likely_have_an_allergy_as_well

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Apple's Weird Refurbished Ebay Store Is Gone

Shoppers looking for the best price on Apple stuff recently may have noticed a mysterious Ebay store selling official Apple refurbs for less than Apple itself. Although Apple never confirmed their involvement, it was widely believed that they were behind Refurbished_Outlet because it sold official Apple refurbs with genuine Applecare. Today, there are no more products for sale through Refurbished_Outlet, and the store page brings you to an FAQ. More »

Source: http://feeds.gawker.com/~r/gizmodo/full/~3/r4TrVmy58TY/apples-weird-refurbished-ebay-store-is-gone

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Email marketing | Internet Marketing

Project Description:
If you want you can perform any of the task below or both.
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Task no 1

I need to design an email for my auction website.

Which would be used for bulk email sending for the publicity of a website, details would be provided on request.

Task no 2 will use your own email collection.

You

If you can send 1, 000, 000 emails to europe and usa only.

? Create email marketing campaigns to promote products or services.
? Ensure marketing message is conveyed clearly and delivered properly to prospects.
? Ensure messages are sent in proper form and template.
? Proofread emails for clarity, grammar, and spelling.
? Develop a personalization strategy.
? Include specific graphics, incentives, and detailed descriptions.
? Review messages for brevity.
? Send messages to those who have opted in for messages.
? Ensure messages are mobile-friendly.
? Create database of emails for lead generation.
? Include persuasive 'call-to-actions' in advertisements and promotions.
? Place orders for products.
? Design and write press releases.
? Track and analyze direct and interactive marketing campaigns.
? Use statistical analysis and reports to create campaigns.
? Coordinate and monitor the maintenance, integrity, and security of several databases.
? Develop and code the list segmentation for all direct and interactive marketing campaigns and communicate requirements to the primary database vendor.

I need lead genration.
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Cearly define if you would be performing
Task 1 or Task 2 or both.

How much is maximum time you required.

[Removed by Freelancer.com admin; exchanging of contact information is prohibited unless the project is already awarded.]

Your Availability
Have you done such work beofore if yes let me have the reference.

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Don't bother to apply if you have not work on odesk before.

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Skills required:
Internet Marketing

Source: http://www.freelancer.com/projects/Internet-Marketing/Email-marketing.4389490.html

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College athletes twice as likely to have depression than retired collegiate athletes

Apr. 2, 2013 ? A survey of current and former college athletes finds depression levels significantly higher in current athletes, a result that upended the researchers' hypothesis. The finding published in Sports Health suggests the need for more research to understand depression among college athletes.

"We expected to see a significant increase in depression once athletes graduated, but by comparison it appears the stress of intercollegiate athletics may be more significant than we and others anticipated," says the study's senior investigator Daniel Merenstein, MD, an associate professor of family medicine and human science at Georgetown University Medical Center.

While no research exists on depression in athletes who have recently graduated from college, the researchers hypothesized that the changes in lifestyle and loss of personal identity would put former college athletes at an increased risk for depression.

"College athletes often derive their personal identity from their sport, focusing a lot of their time on athletics in college," the study authors write. "They are often surrounded by other athletes and frequently have an athletic identity from their peers who recognize them on campus as an athlete."

The authors also point out that after college athletics, there is a loss of social support from teammates, coaches and advisors, and that former athletes may not maintain peak physical condition -- all possible factors for depression.

To examine their hypothesis, the researchers sent surveys to 663 athletes; 163 former and 117 current athletes from nine different universities took part in the study. All had participated in Division I NCAA sponsored sports. Graduated athletes represented 15 different sports and current athletes represented 10.

The analysis of the surveys revealed that nearly 17 percent of current college athletes had scores consistent with depression -- double that of retired college athletes (eight percent).

Merenstein, a family medicine physician, and his colleagues suggest that stressors experienced by college athletes such as overtraining, injury, pressure to perform, lack of free time or stress from schoolwork could contribute to increased susceptibility to depression.

"College in general is a potentially stressful time for many students. The additional stress of playing high-level sports appears to add to that stress," he says.

Merenstein advises parents, friends and coaches to be aware of changes in behavior, weight and sleep of college athletes, and of all students.

In addition to Merenstein, authors of the study include Jared Cohen, a medical student at Temple University and Sabrina Weigand, a medical student at Tulane University. At the time of the study, both were students in the department of human science at Georgetown University School of Nursing & Health Studies.

The study was supported by the department of family medicine. The authors report having no personal financial interests related to the study.

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The above story is reprinted from materials provided by Georgetown University Medical Center.

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Journal Reference:

1. S. Weigand, J. Cohen, D. Merenstein. Susceptibility for Depression in Current and Retired Student Athletes. Sports Health: A Multidisciplinary Approach, 2013; DOI: 10.1177/1941738113480464

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/most_popular/~3/mRf-Q2Oc1nw/130402150149.htm

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Newly approved blood thinner may increase susceptibility to some viral infections

Apr. 1, 2013 ? A study led by researchers at the University of North Carolina indicates that a newly approved blood thinner that blocks a key component of the human blood clotting system may increase the risk and severity of certain viral infections, including flu and myocarditis, a viral infection of the heart and a significant cause of sudden death in children and young adults.

For the past 50 years, people with the heartbeat irregularity, atrial fibrillation, and others at increased risk for forming potentially life-threatening blood clots have been given the anticoagulant drug warfarin. Recently, the U.S. Food and Drug Administration approved the use of the blood-thinner Dabigatran etexilate (called Pradaxa?) for atrial fibrillation patients. The drug inhibits thrombin, the body's central coagulation activator of the blood clotting system.

In blocking thrombin activity, the drug disturbs the protease cascade of molecular events that normally occurs in coagulation. While clot formation is reduced, the new study shows it may also cause an unintended consequence. "Our findings show that blocking thrombin reduces the innate immune response to viral infection," says study senior author Nigel Mackman, PhD, the John C. Parker Distinguished Professor of Medicine in the division of hematology and director of the UNC McAllister Heart Institute. "The use of the new generation of blood thinners might increase the risk and severity of flu and myocarditis."

A report of the research appears in the March 2013 issue of The Journal of Clinical Investigation.

Mackman points out that viral infections such as dengue fever trigger activation of the coagulation system but it was considered a bad thing. He says studies on bacterial infections have found that the last product of the "clotting cascade" (the process that occurs in blood clot formation) -- fibrin -- helps activate immune cell macrophages that boosts the immune system.

"But it seems that the antiviral mechanism of the clotting system is not via fibrin but rather via thrombin; namely, its activation of protease activated receptor proteins such as PAR-1," says Mackman. "The new study was aimed at finding out if PAR-1 plays any role in virus infections, a question of importance to the use of Pradaxa? and the development of antithrombotic drugs that target PAR-1 on platelets."

To find the answer, Mackman and colleagues used mice in which the PAR-1 gene is deleted and subjected then to infection with a virus that causes myocarditis. They found that loss of PAR-1 mediated signaling after infection with the cardiotrophic virus resulted in increased viral buildup in the heart, cardiac injury and, later, increased impairment of heart function.

Moreover, the absence of PAR-1 signaling was associated with a slower response to the virus of the innate immune soon after viral infection. The innate immune system provides early defense against disease causing organisms. The defense is almost immediate.

The researchers treated normal mice with Pradaxa?. They showed that thrombin inhibition increased cardiac virus load and cardiac injury after viral infection in a similar manner to a deficiency of PAR-1. In addition, they infected the PAR-1 deficient mice with influenza A and found that PAR-1 signaling was important in controlling the virus load in the lung in the early phase after infection. These results suggest that thrombin and PAR-1 mediate important early antiviral signals after infection.

"Pradaxa? inhibits clot formation by reducing fibrin deposition and platelet aggregation." said Mackman. "Importantly, Pradaxa? might not only facilitate significant lifesaving effects in reducing cardiac death but may also interfere with other processes in the body.

"The results we generated were completely unexpected and in fact our hypothesis was that PAR-1 deficient mice would be protected from viral myocarditis because they would have reduced inflammation," Mackman added. "We are now determining if the traditional long term anticoagulant warfarin has the same effect on viral infection or is this specific to the new blood thinner."

The majority of the study was a collaboration between the Mackman group at UNC and the Charit? -- Universit?tsmedizin in Berlin, Germany, and other groups at UNC, including at the Gillings School of Global Public Health, and across the USA.

The first-author is Silvio Antoniak, PhD, a postdoctoral researcher in Mackman's lab. Other co-authors from Mackman's lab were A. Phillip Owens III, PhD; Martin Baumnacke, MD; and Julie C. Williams, PhD.

The study was supported by the Myocarditis Foundation through a research grant to Silvio Antoniak. Additional funds were provided by the National Heart, Lung and Blood Institute (NHLBI), a component of the National Institutes of Health.

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The above story is reprinted from materials provided by University of North Carolina Health Care.

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Journal Reference:

1. Silvio Antoniak, A. Phillip Owens, Martin Baunacke, Julie C. Williams, Rebecca D. Lee, Alice Weith?user, Patricia A. Sheridan, Ronny Malz, James P. Luyendyk, Denise A. Esserman, JoAnn Trejo, Daniel Kirchhofer, Burns C. Blaxall, Rafal Pawlinski, Melinda A. Beck, Ursula Rauch, Nigel Mackman. PAR-1 contributes to the innate immune response during viral infection. Journal of Clinical Investigation, 2013; 123 (3): 1310 DOI: 10.1172/JCI66125

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Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/ANitGbFwha4/130401132058.htm

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'Miracle foods': Can they decrease the risk of cancer?

Apr. 1, 2013 ? Cancer is a disease that invokes fear, so it is not surprising that the public is eager to identify ways to decrease the risk. The media often features information on "Miracle Foods" and publicizes whether these foods can actually decrease the risk of cancer.

"Reality Check: There is No Such Thing as a Miracle Food," published in Volume 65, Issue 2, 2013 of Nutrition and Cancer: An International Journal, is a commentary written by the University of Minnesota's Maki Inoue-Choi, Sarah Oppeneer, and Kim Robien that calls on both researchers as well as media sources to consider the validity of multiple studies as opposed to singular studies before assuming that media information is factual.

"Nutritional scientists and epidemiologists should be cognizant of the public health messages that are taken away from their individual studies and not sensationalize the findings or contribute to the media frenzy around a single study," the authors believe.

The authors mention two separate studies that theorize a decreased risk of ovarian cancer due to flavonoids in red onions and omega-3 in sea bass. Both of these studies were reported as fact on a popular television talk show. The authors assert that with further research, three other studies would have been found that can disprove the findings reported as true.

"The public needs more information about the effect of diet as a whole on cancer risk, as well as the importance of achieving and maintaining an ideal body weight, regular physical activity, and avoiding a sedentary lifestyle," the authors wrote. ?

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The above story is reprinted from materials provided by Taylor & Francis, via AlphaGalileo.

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Journal Reference:

1. Maki Inoue-Choi, Sarah J. Oppeneer, Kim Robien. Reality Check: There is No Such Thing as a Miracle Food. Nutrition and Cancer, 2013; 65 (2): 165 DOI: 10.1080/01635581.2013.748921

Note: If no author is given, the source is cited instead.

Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.

Source: http://feeds.sciencedaily.com/~r/sciencedaily/health_medicine/nutrition/~3/M8ou2yj1lio/130401090605.htm

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?Buckwild? Star Shain Gandee Found Dead UPDATE (VIDEO)

“Buckwild” Star Shain Gandee Found Dead UPDATE (VIDEO)

“Buckwild” star Shain Gandee was found dead along with two other people in West Virginia. The MTV reality star had been reported missing since Sunday. The deaths are currently under investigation, but no foul play appears to be involved. Gandee, 21, was reportedly found dead along with two other people in a vehicle in Sissonville, ...

“Buckwild” Star Shain Gandee Found Dead UPDATE (VIDEO) Stupid Celebrities Gossip Stupid Celebrities Gossip News

Source: http://stupidcelebrities.net/2013/04/buckwild-star-shain-gandee-found-dead-video/

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